彭景楠, 张华中, 李常乐, 李兴海, 祁之秋. 1S,2R-((3-溴苯乙基) 氨基)-N-(4-氯-2-三氟甲基苯基) 环己烷基-1-磺酰胺对灰葡萄孢的抑菌活性及作用方式[J]. 农药学学报, 2021, 23(3): 509-514. DOI: 10.16801/j.issn.1008-7303.2021.0055
    引用本文: 彭景楠, 张华中, 李常乐, 李兴海, 祁之秋. 1S,2R-((3-溴苯乙基) 氨基)-N-(4-氯-2-三氟甲基苯基) 环己烷基-1-磺酰胺对灰葡萄孢的抑菌活性及作用方式[J]. 农药学学报, 2021, 23(3): 509-514. DOI: 10.16801/j.issn.1008-7303.2021.0055
    PENG Jingnan, ZHANG Huazhong, LI Changle, LI Xinghai, QI Zhiqiu. Antifungal activity of compound 1S,2R-((3-bromophenethyl)amino)-N-(4-chloro-2-trifluoromethylphenyl) cyclohexane-1-sulfonamide against Botrytis cinerea and its mode of action[J]. Chinese Journal of Pesticide Science, 2021, 23(3): 509-514. DOI: 10.16801/j.issn.1008-7303.2021.0055
    Citation: PENG Jingnan, ZHANG Huazhong, LI Changle, LI Xinghai, QI Zhiqiu. Antifungal activity of compound 1S,2R-((3-bromophenethyl)amino)-N-(4-chloro-2-trifluoromethylphenyl) cyclohexane-1-sulfonamide against Botrytis cinerea and its mode of action[J]. Chinese Journal of Pesticide Science, 2021, 23(3): 509-514. DOI: 10.16801/j.issn.1008-7303.2021.0055

    1S,2R-((3-溴苯乙基) 氨基)-N-(4-氯-2-三氟甲基苯基) 环己烷基-1-磺酰胺对灰葡萄孢的抑菌活性及作用方式

    Antifungal activity of compound 1S,2R-((3-bromophenethyl)amino)-N-(4-chloro-2-trifluoromethylphenyl) cyclohexane-1-sulfonamide against Botrytis cinerea and its mode of action

    • 摘要: 研究了磺酰胺类化合物1S,2R-((3-溴苯乙基) 氨基)-N-(4-氯-2-三氟甲基苯基) 环己烷基-1-磺酰胺 (代号SYAUP-CN-26) 的抑菌活性及防治病害的作用方式。结果表明,SYAUP-CN-26可抑制多种植物病原真菌的菌丝生长和孢子萌发,尤以对灰葡萄孢Botrytis cinerea的抑制活性较强,EC50值分别为1.82 μg/mL和14.98 μg/mL。20 μg/mL的SYAUP-CN-26处理能显著降低灰葡萄孢的产孢量、产菌核量,增加单菌核重。经该化合物处理过的灰葡萄孢孢子及菌丝致病力均降低。200 μg/mL的SYAUP-CN-26对番茄灰霉病的保护效果和治疗效果分别为83.11%和47.52%,保护作用优于治疗作用。

       

      Abstract: The antifungal activity of sulfonamide compound 1S, 2R-((3-bromophenethyl)amino)-N-(4-chloro-2-trifluoromethylphenyl)cyclohexane-1-sulfonamide (SYAUP-CN-26) against Botrytis cinerea was determined and its mode of action for controlling diseases was investigated. The results showed that SYAUP-CN-26 inhibited hyphal growth and spore germination of some plant pathogenic fungi, especially for B. cinerea with the EC50 value of 1.82 μg/mL and 14.98 μg/mL, respectively. The spore production, sclerotic production were reduced significantly, and the single sclerotic weigh was increased significantly under the treatment of 20 μg/mL of SYAUP-CN-26. The pathogenicity of B. cinerea treated by SYAUP-CN-26 was significantly lower than that of the control. SYAUP-CN-26 at 200 μg/mL provided control efficacies of 83.11% and 47.52% for protective and curative spraying against tomato gray mold, respectively which showed that SYAUP-CN-26 possessed better protective activity than curative activity.

       

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