Abstract: Pesticides, plant protection machinery and application technology are the three pillars of plant chemical protection, of which application technology is the key link between pesticides and plant protection machinery. It is the "last mile" from pesticide research to field application. The scientific use of pesticides is not a simple pharmacological problem of pesticide selection and application dosage, but involves plant protection, agricultural mechanics, meteorology and other disciplines, forming an interdisciplinary combination of systemic engineering. This paper presents a review of pesticide droplet atomization and movement characteristics, deposition and distribution status, loss and drift behavior, and the relationship between pest behavior and pesticide droplet atomization movement and deposition distribution. The purpose of summarizing the theoretical and practical experiences in these areas is to improve the standards and quality of plant protection machinery, pesticide utilization, control effects and food safety, as well as reducing the negative impacts of pesticides. In addition, these theories and practices provide technical methods and equipment support to improve the quality and efficiency of crops and to protect agroecological and human environments.