Synthesis and antibacterial and fungicidal activity of 3-oxo-N-arylbenzodisothiazole-2(3H)-carboxamides

Thirteen 3-oxo-N-arylbenzodisothiazole-2(3H)-carboxamide derivatives were synthesized via reaction of 1,2-benzisothiazol-2(3H)-one with substituted phenyl isocyanate.Among them nine compounds were not reported.Their structures were confirmed by elemental analyses,IR and 1H NMR.Priliminary bioassays showed that some of the compounds exhibit 80%-100% inhibition rate against Bacillus subtilis and Botryodiplodia theobromae at the concentration of 50 mg/L.