Abstract: A mult iresidue method for determination of 14 organopho sphorous pest icides in some chinese medicinal plants was developed. These compounds were microw ave-assisted extracted (MAE) with acetone at 90W for 5 min. A fter cleanup by C18-Silica gelsolid phase extraction, these pho spho rous pesticides were determ ined by capillary gas chromatography with flame photometric detector. The conditions of MAE and cleanup were optimized. The recoveries were 85%～102.7% with RSD 1.2 %～8.1%. Them inimum detectable levels were 0.004 mg/kg( dichlorvos )～0.026 mg/kg(profenofos). The recoveries were correspondent with that from conventional shake extraction.