Abstract: Chinese herbal medicine is the strategic resource and the basis for the development of traditional Chinese medicine. Dendrobium officinale, " 8 famous Chinese herbal medicine” and other Chinese herbal medicinal materials production in Zhejiang play an important position in China. With the rapid development in recent years, the pest damage, the pesticide pollution and residue due to improper use have become risks to the quality and safety of Chinese herbal medicines. Since the relative researches focused on the description of pest’s symptoms and field trails of control were a little later and fewer. And the basic researches were very weak. There was few registered pesticides for the farmers. And nearly no standards of pesticide residues and the safe usage procedures of pesticides were provided. The corresponding resistance research was rare. Therefore, that there were many works need to be done for the scientific application of pesticides. This review summarized the status of chemical control on the pests of characteristic Chinese herbal medicines in Zhejiang Province in the past 20 years, including aspects such as systematical identification of the pests, assay pesticides in laboratory and fields, residues and resistance. According to the weaknesses and major problems, we proposed that the basic researches of pests control and quality safety, the screening of new pesticides, pesticides registration and relative standards, pesticides resistance monitoring and management, the research and promotion of comprehensive management technology, safe application of pesticides should be strengthened and accelerated in order to supply theoretical basis and technological supports for the pests control of Chinese herb and to provide references for chemical control of pests on other small crops.