Abstract:
Through different synthetic routes, 22 novel 4
H-pyrazolo3,4-
d1,2,3 triazine-4-ones with bulky substituents were synthesized using 1-(substituted) phenyl-5-amino-1
H-pyrazole-4-formate or 1-
tert-butyl-5-amino-1
H-pyrazole-4-carbonyl chloride and 2-methyl-4-propargyl-6-amino-7-fluoro-2
H-benzo
b1,4-oxazine-3(4
H)-one as starting materials. Their structures were confirmed by
1H NMR and HRMS. Preliminary results showed that most of the target compounds displayed herbicidal activities at the dosage of 375 g/hm
2. The inhibition rates of
4h ,
4i and
4j against
Amaranthus retroflexus were nearly 100%.