N-取代苯并噁嗪酮类化合物的合成及其生物活性

Synthesis and Biological Activity of N-Substituted 4H-benzoxazin-3-one

摘要: 为寻求具有高生物活性的新农药化合物,以邻氨基苯酚为原料设计合成了N-取代的苯并噁嗪酮类化合物18个,其化学结构经1H NMR及元素分析确证。初步的生物活性测试结果表明,部分化合物具有良好的除草活性,如化合物 c3、c5、c6、c7和c8 在浓度为100 mg/L时对苋菜Ambrosia tricolor Linn. 的抑制率达90%。

Abstract: In search of novel compounds with high biological activities,18 N-substituted benzoxazinone derivatives were designed and synthesized.Their chemical structures were confimed by 1H NMR and elemental analysis.Preliminary bioassays showed that some of them have good herbicidal activity.The inhibition rate of c3,c5,c6,c7 and c8 to Ambrosia tricolor Linn. was up to 90% at the concentration of 100 mg/L.