Abstract: Liquid phase microextraction(LPME) is one of novel sample pretreatment techniques which has many advantages such as quick,simple,economic,highly selective and accurate,less-solvent consuming and environmental friendly.It can be matched easily with most of analytical instruments.It includes several types such as single drop microextraction(SDME),hollow fiber liquid phase microextraction(HF-LPME),dispersive liquid-liquid microextraction(DLLME),solidified floating organic drop microextraction(SFODME),continuous-flow microextraction(CFME) and directly-suspended droplet microextraction (DSDME) etc.It is a very potential sample pretreatment technique for theoretic and application studies.In this review,the historical development and overview of these miniaturized liquid phase extraction methodologies were discussed and a comprehensive collection of application of these methods for preconcentration and determination of pesticide residue in various matrices were summarized.