Abstract: An analytical method to detect chlorantraniliprole residue in corn was established.The sample was extracted by acetonitrile and dichloromethane,cleaned by PSA dispersive solid-phase extraction and separated by ultra performance liquid chromatography with photo-diode array detector at 254 nm,quantified with external standard method.When the spiked levels were 0.02-1 mg/kg,the average recoveries of the method ranged from 81% to 91%,the relative standard deviation ranged from 6.2% to 14.0%,the limit of detection(LOD) was 0.02 ng,the limit of quantification(LOQ) was 0.02 mg/kg.The method was simple and reliable,meet with the requirement of pesticide residues analysis,and could be applied for determining chlorantraniliprole residue in corn.