Abstract: In order to study the residual behavior and safety of abamectin in cabbage mustard, leaf mustard and turnip, an analytical method for the determination of abamectin residue in these three cruciferous vegetables was developed by using high performance liquid chromatography. The samples were extracted by acetone, purified by C18 column, and detected by HPLC-VWD. Residual dissipation dynamics and final residue levels of abamectin in cabbage mustard, leaf mustard and turnip from six experimental sites (Yantai in Shandong Province, Baoding in Hebei Province, Shaoxing in Zhejiang Province, Guiyang in Guizhou Province, Harbin in Heilongjiang Province and Suzhou in Anhui Province) were determined. The results showed the dissipation of abamectin in cabbage mustard, leaf mustard and turnip were rapid, with half-lives varied from 0.3-0.6 d, 2.2-3.1 d and 0.8-1.0 d, respectively. The residual contents of abamectin in three cruciferous vegetables decreased according to the first-order kinetics equation, which indicated that abamectin is an easily degradable pesticide.