Abstract: The use of inorganic materials as carriers to carry pesticides can effectively improve the control effect and effective utilization rate of pesticides. Calcium carbonate has the advantages of good biocompatibility, good pH response, low environmental toxicity and easy degradation, and its application in pesticide delivery system has become a research hotspot at home and abroad. In this paper, the preparation, drug loading method and advantages and disadvantages of calcium carbonate pesticide drug loading system are introduced, and the research progress of calcium carbonate pesticide drug loading system in the agricultural field is reviewed, and the problems encountered in the application process and possible challenges are analyzed, aiming to provide reference for the research and application of calcium carbonate pesticide drug loading system.