Abstract: After selection for 12 generations in the laboratory, Spodoptera exigua(Hübner)showed 5.47-fold resistance to tebufenozide. The resistance strain showed low cross-resistance to methoxyfenozide, but it showed no cross-resistance to cyhalothrin, deltamethrin, beta-cypermethrin, phoxim, chlorpyrifos, methomyl, emamectin, fipronil and chlorfluazuron,with resistance ratios ranged from 0.83- to 1.63-fold.