Abstract:
Nine novel 2-(1-(3-chloro pyridin-2-yl)-3, 5-dimethyl-1
H-pyrazol-4-yl) acetic acid derivatives
B1 -
B9 were synthesized from acetylacetone, ethyl bromoacetate and 2, 6-dichloropyridine. The synthesis route included a series of reactions such as substitution, alkylation, cyclization, hydrolysis, and acidification condensation. The chemical structures were characterized by
1H NMR and MS. Preliminary bioassay showed that most of the above compounds displayed herbicidal activities at the concentration of 150 g/hm
2. The inhibition rates of
B2, B3, B6 and
B8 against
Abutilon theophrasti Medicus,
Amaranthus retroflexus and
Amaranthus lividus L. were nearly 100%.