Abstract: In order to improve the maximum residue limits (MRLs) standards system for veterinary drugs in aquatic products in Mainland China and promote the exchange and cooperation in quality and safety supervision of aquatic product between two sides of the Taiwan Straits, the MRLs standards among Mainland China, Taiwan China, Codex Alimentarius Commission (CAC), Japan, USA and EU are compared and analyzed. The results show that, (1) duplication of regulatory exista in the MRLs standards of Mainland China and the MRLs standard in No. 235th is the most perfect in Mainland China, which was announced by ministry of agriculture; (2) the MRLs standards in Taiwan China is higher than that in Mainland China; (3) the residue standards of Mainland China and Taiwan China is not consistent with international standards; (4) the MRLs standards of Mainland China and Taiwan China are stricter and more meticulous than that of CAC. However, the standards are not as detailed and scientific as those in Japan and EU. Last but not the least, this paper puts forward the policy countermeasures on improving the MRLs standard system of veterinary drug residues in aquatic product and strengthening the cooperation between both sides of the Taiwan Straits.