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中国农药创制概述与展望

芦志成 张鹏飞 李慧超 关爱莹 刘长令

芦志成, 张鹏飞, 李慧超, 关爱莹, 刘长令. 中国农药创制概述与展望[J]. 农药学学报, 2019, 21(5-6): 551-579. doi: 10.16801/j.issn.1008-7303.2019.0086
引用本文: 芦志成, 张鹏飞, 李慧超, 关爱莹, 刘长令. 中国农药创制概述与展望[J]. 农药学学报, 2019, 21(5-6): 551-579. doi: 10.16801/j.issn.1008-7303.2019.0086
LU Zhicheng, ZHANG Pengfei, LI Huichao, GUAN Aiying, LIU Changling. Overview and prospect of agrochemical discovery in China[J]. Chinese Journal of Pesticide Science, 2019, 21(5-6): 551-579. doi: 10.16801/j.issn.1008-7303.2019.0086
Citation: LU Zhicheng, ZHANG Pengfei, LI Huichao, GUAN Aiying, LIU Changling. Overview and prospect of agrochemical discovery in China[J]. Chinese Journal of Pesticide Science, 2019, 21(5-6): 551-579. doi: 10.16801/j.issn.1008-7303.2019.0086

中国农药创制概述与展望

doi: 10.16801/j.issn.1008-7303.2019.0086
基金项目: 国家重点研发计划 (2016YFD0300709)
详细信息
    作者简介:

    芦志成,男,助理工程师,主要从事新农药创制,E-mailluzhicheng@sinochem.com

    通讯作者:

    关爱莹,共同通信作者 (Co-author for correspondence),女,高级工程师,主要从事新农药创制,E-mailguanaiying@sinochem.com

    刘长令,通信作者 (Author for correspondence),男,教授级高级工程师,主要从事新农药创制,E-mailliuchangling@vip.163.com

  • 中图分类号: TQ450.1

Overview and prospect of agrochemical discovery in China

  • 摘要: 中国是农业大国,而现代农业生产离不开农药。中国的农药工业经过近70年的发展,已从仿制国外品种到仿创结合再到自主创新的道路上逐渐发展壮大起来。在建国70周年之际,本文简要总结了中国农药创制的发展历史,对中国现有大多数农药创制品种从其化学结构、性能、创制经纬、作用机理以及专利和登记情况进行了介绍,并做了进一步的展望。
  • 1  中国专利法实施前部分农药代表品种

    1.  Representative pesticides before the implementation of the patent law of China

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    表  1  中国创制或开发农药一览表

    Table  1.   List of pesticide discovered or developed in China

    农药种类
    Classification of pesticide
    中(英)文名称
    Chinese (English) name
    CAS 号
    CAS registry number
    专利申请日
    Date of filing
    原(母)药登记号
    Drug registration number
    杀菌剂(含杀细菌剂和抗病毒剂)
    Fungicides (including bactericides and virucides)
    金核霉素 aureonuclemycinb 123970-01-4 1987-03-18 LS20021932 (过期 overdue)
    宁南霉素 ningnanmycinb 156410-09-2 1993-04-23 PD20097120
    氟吗啉 flumorpha 211867-47-9 1996-08-21 PD20060039
    烯肟菌酯 enoxastrobina 238410-11-2 1998-02-10 PD20070339
    烯肟菌胺 fenaminstrobina 366815-39-6 2000-02-24 PD20095214
    噻菌铜 thiodiazole-copperb 3234-61-5 1999-01-11 PD20086025
    噻唑锌 zinc-thiazoleb 3234-62-6 2000-12-15 PD20160049
    啶菌噁唑 pyrisoxazolea 847749-37-5 1999-07-14 PD20080773
    氰烯菌酯 phenamacrilb 39491-78-6 2001-05-08 PD20121663
    长川霉素 ascomycinb 104987-12-4 2001-10-08 LS20072567 (过期 overdue)
    申嗪霉素 phenazino-1-carboxylic acid 2538-68-3 2002-02-08 PD20110314
    苯醚菌酯 ZJ-0712 852369-40-5 2003-03-25 PD20151573
    氟唑活化酯 B2-a 864237-81-0 2003-05-16 LS20150091 (过期 overdue)
    丁吡吗啉 pyrimorphb 868390-90-3 2003-07-01 PD20181610
    丁香菌酯 coumoxystrobina 850881-70-8 2003-11-11 PD20161260
    唑菌酯 pyraoxystrobina 862588-11-2 2004-02-20 PD20181599
    唑胺菌酯 pyrametostrobina 915410-70-7 2005-05-26 LS20110235 (过期 overdue)
    氯啶菌酯 triclopyricarba 902760-40-1 2005-02-06 PD20161257
    毒氟磷 882182-49-2 2005-04-04 PD20160339
    甲噻诱胺 methiadinilb 908298-37-3 2006-02-20 PD20170015
    补骨脂种子提取物 isobavachalconeb 20784-50-3 2008-01-25 PD20190058
    氟醚菌酰胺 fluopimomidea 1309859-39-9 2010-09-07 PD20170010
    杀虫剂(含杀螨剂)
    Insecticides (including acaricides)
    苦皮藤素 celangulinb 139979-81-0 1992-11-19 PD20101575
    硝虫硫磷 89-1 171605-91-7 1993-01-12 PD20080777
    氯胺磷 chloramine phosphorusb 73447-20-8 1997-06-24 LS20051337 (过期 overdue)
    氟螨 F1050 259726-10-8 1997-12-15 LS20031728 (过期 overdue)
    硫肟醚 sulfoximeb 355143-88-3 1999-09-10 LS20041355 (过期 overdue)
    硫氟肟醚 thiofluoximateb 860028-12-2 2003-12-12 LS20140310 (过期 overdue)
    右旋反式氯丙炔菊酯 399572-87-3 1999-12-13 WP20170145
    呋喃虫酰肼 fufenozideb 467427-81-1 2001-03-26 PD20121672
    丁虫腈 flufiprolea 704886-18-0 2002-07-30 PD20120414
    氯噻啉 imidaclothizb 105843-36-5 2002-10-21 PD20082528
    哌虫啶 IPP-44 948994-16-9 2004-11-23 PD20171435
    氯氟醚菊酯 meperfluthrina 915288-13-0 2008-07-07 WP20110065
    四氯虫酰胺 tetrachlorantraniliprolea 1104384-14-6 2008-07-07 PD20171752
    戊吡虫胍 guadipyrb 1376342-13-0 2008-11-25 LS20170095 (过期 overdue)
    环氧虫啉 1185987-44-3 2008-12-17 LS20170342 (过期 overdue)
    环氧虫啶 cycloxapridb 1281863-13-5 2008-12-19 PD20184015
    氯溴虫腈 HNPC-A3061 890929-78-9 2009-06-29 LS20140332 (过期 overdue)
    乙唑螨腈 SYP-9625 1253429-01-4 2010-04-27 PD20181623
    除草剂
    Herbicides
    单嘧磺隆 monosulfuronb 155860-63-2 1994-12-07 PD20070369
    单嘧磺酯 monosulfuron-esterb 175076-90-1 1994-12-07 PD20130372
    双甲胺草磷 H-9201 189517-75-7 1996-11-26 LS20051937 (过期 overdue)
    氯酰草膦 clacyfosa 215655-76-8 1997-04-30 LS20071853 (过期 overdue)
    甲硫嘧磺隆 methiopyrsulfuronb 441050-97-1 2000-05-11 LS20060244 (过期 overdue)
    丙酯草醚 pyribambenz-propylb 420138-40-5 2000-10-16 PD20141891
    异丙酯草醚 pyribambenz-isopropylb 420138-41-6 2000-10-16 PD20141888
    二氯喹啉草酮 G-18 1350901-36-8 2011-05-10 PD20184028
    环吡氟草酮 1855929-45-1 2015-11-06 PD20184021
    双唑草酮 1622908-18-2 2015-11-06 PD20184018
    植物生长调节剂
    Plant growth regulators
    菊胺酯 WD-5 172351-12-1 1993-02-18 LS20030206 (过期 overdue)
    苯哒嗪丙酯 BAU9403 78778-15-1 1998-11-16 LS20020926 (过期 overdue)
    呋苯硫脲 fuphenthioureab 1332625-45-2 1999-12-15 LS20053285 (过期 overdue)
    14-羟基芸苔素甾醇
    14-hydroxylated brassinosteroidb
    457603-63-3 2012-01-18 PD20171724
    注:a 表示获得ISO通用名称;b表示未获得ISO通用名称,是中国英文名称。Note: a is ISO common name. b is no ISO common name, the name is approved in China.
    下载: 导出CSV
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