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生物检材中有机磷农药代谢物检测技术研究进展

张成龙 国菲 杨瑞琴 李鹏

张成龙, 国菲, 杨瑞琴, 李鹏. 生物检材中有机磷农药代谢物检测技术研究进展[J]. 农药学学报. doi: 10.16801/j.issn.1008-7303.2021.0070
引用本文: 张成龙, 国菲, 杨瑞琴, 李鹏. 生物检材中有机磷农药代谢物检测技术研究进展[J]. 农药学学报. doi: 10.16801/j.issn.1008-7303.2021.0070
Chenglong ZHANG, Fei GUO, Ruiqin YANG, Peng LI. Research progress on detection technology of organophosphorus pesticide metabolites in biological samples[J]. Chinese Journal of Pesticide Science. doi: 10.16801/j.issn.1008-7303.2021.0070
Citation: Chenglong ZHANG, Fei GUO, Ruiqin YANG, Peng LI. Research progress on detection technology of organophosphorus pesticide metabolites in biological samples[J]. Chinese Journal of Pesticide Science. doi: 10.16801/j.issn.1008-7303.2021.0070

生物检材中有机磷农药代谢物检测技术研究进展

doi: 10.16801/j.issn.1008-7303.2021.0070
详细信息
    作者简介:

    张成龙,男,硕士研究生,E-mail:Zhangchenglong3713@163.com

    通讯作者:

    杨瑞琴,通信作者 (Author for correspondence),女,博士,教授,研究方向为刑事科学技术,E-mail:Yangruiqin@ppsuc.edu.cn

    李 鹏,共同通信作者 (Co-corresponding author),男,博士研究生,高级工程师,研究方向为理化检验,E-mail:lp434434@163.com

  • 中图分类号: X592;O657

Research progress on detection technology of organophosphorus pesticide metabolites in biological samples

  • 摘要: 有机磷农药代谢物检测分析在有机磷农药中毒、投毒案件定性,临床诊断,生物监测等方面发挥着重要作用。发展精确检测痕量甚至超痕量有机磷农药代谢物的技术,建立检测生物样品复杂基质中有机磷农药代谢物的方法,成为法庭科学领域亟待解决的问题之一。目前国内外常见的实验室检测方法有气相色谱、气相色谱-质谱联用、液相色谱-质谱联用等,本文重点综述了这些检测方法的研究进展,血液、尿液等生物检材所需的液-液萃取、固相萃取和QuEChERS等前处理技术以及毛发生物检材所需的固-液萃取等前处理技术。此外,本文还介绍了荧光探针法、免疫分析法、生物传感器法等快速检测技术的原理及应用进展,并对现有检测技术存在的问题进行了总结。
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  • 收稿日期:  2020-10-13
  • 录用日期:  2021-03-01
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