方运玲, 孙爽, 申阅, 何亚文. 微生物源农药申嗪霉素的研制与应用[J]. 农药学学报, 2014, 16(4): 387-393. DOI: 10.3969/j.issn.1008-7303.2014.04.03
    引用本文: 方运玲, 孙爽, 申阅, 何亚文. 微生物源农药申嗪霉素的研制与应用[J]. 农药学学报, 2014, 16(4): 387-393. DOI: 10.3969/j.issn.1008-7303.2014.04.03
    FANG Yunling, SUN Shuang, SHEN Yue, HE Yawen. Progress on the development and application of biopesticide Shenqinmycin[J]. Chinese Journal of Pesticide Science, 2014, 16(4): 387-393. DOI: 10.3969/j.issn.1008-7303.2014.04.03
    Citation: FANG Yunling, SUN Shuang, SHEN Yue, HE Yawen. Progress on the development and application of biopesticide Shenqinmycin[J]. Chinese Journal of Pesticide Science, 2014, 16(4): 387-393. DOI: 10.3969/j.issn.1008-7303.2014.04.03

    微生物源农药申嗪霉素的研制与应用

    Progress on the development and application of biopesticide Shenqinmycin

    • 摘要: 申嗪霉素是中国自主研发的一种新型微生物源农药,具有高效、安全、广谱等特点,其主要成分是甜瓜根际促生菌M18产生的次级代谢产物吩嗪-1-羧酸。文章重点就申嗪霉素产生菌M18的分离及其代谢产物的鉴定、申嗪霉素生物合成及调控机理最新研究进展、申嗪霉素高产工程菌株的构建和产业化、以及申嗪霉素大田防病试验结果及推广应用情况等进行详细综述,并对其抗菌作用机理进行探讨,旨在为申嗪霉素的生物合成机理研究、遗传和代谢改造以及推广应用提供参考。

       

      Abstract: Shenqinmycin is a newly developed biopesticide containing the secondary metabolite phenazine-1-carboxylic acid (PCA) produced by Pseudomonas sp. M18. The discovery and characterization of Pseudomonas sp. M18 as well as the identification of metabolites were firstly introduced; The progress on Shenqinmycin biosynthetic mechanism and regulatory network was then summarized; The construction of high-yield engineered strain and industrialization of Shenqinmycin were further introduced; Finally, the application of Shenqinmycin in plant disease control and possible antifungal mechanisms of shenqinmycin were discussed.

       

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