磷氮霉素PN-2的分离鉴定及活性研究初报

The Primary Study on Isolation and Identification of Antibiotic Phosphazomycin

摘要: 在农用抗生素的筛选中,得到一株活性菌株,菌号为Streptomyces SPRI-82715,通过发酵、吸附、提取等手段分离得到6个活性化合物,其中磷氮霉素(PN-2)为主要成分。经过 UV、IR、MS、NMR等手段鉴定,该系列化合物的结构与文献报道的phosphazomycin系列化合物相似。

Abstract: In screening antibiotics for agricultural use, an active strain of Streptomyces SPRI-82715 was obtained and six compounds (PN-0, PN-1, PN-2, PN-3, PN-4, PN-5) with fungicidal activities were separated from the fermentation broth of the strain. The data of UV, IR, MS, NMR of the compound PN-2 have been analyzed, six substances belong to the classes of phosphazomycin. Identification of PN-2 was reported.