Abstract:
In order to find new active compounds,the structure of 1β,2β,4α,6α,8β,9α,13-hepthydroxy-β-dihydroagarofuran was simplified to be 1β,4α,6α,9α-tetrahydroxy-2β,12-ether-β-dihydroagarofuran,and seven new dihydroagarofuran ether analogues were synthesized using 1β,4α,6α,9α-tetrahydroxy-2β,12-ether-β-dihydroagarofuran as staring materials. Their structures were confirmed by NMR,IR and HRMS spectral data. Bioassay results indicated that diallyl ether and tributyl ether analogues exhibited higher insecticidal activity than Celangulin V against 3rd-instar larvae of Mythimna separata at the concentration of 10 mg/mL.