吡啶衍生物研究 Ⅹ Ⅳ:2-(2-芳氧基吡啶-3-甲酰氧基)丙酸酯的合成及除草活性

Studies on pyridine derivatives(Ⅹ Ⅳ):Synthesis and herbicidal activity of 2-(2-aryloxypyridine-3-carbonyloxy)-propionate

摘要: 以2-氯烟酸和酚类化合物为原料,通过醚化、酯化等反应合成了24个2-(2-芳氧基吡啶-3-甲酰氧基)丙酸酯类化合物,其结构均通过核磁共振氢谱和质谱分析确证。初步除草活性测定结果表明,在100 mg/L剂量下,部分目标化合物对马唐Digitaria adscendens和苘麻Abutilon theophrasti的抑制率可达100％。

Abstract: Twenty four 2-(2-aryloxy pyridine-3-carbonyloxy)propionates were synthesized by etherification,esterification starting from 2-chloroisonicotinic acid and phenoles.All of the structures were comfirmed by 1H NMR and MS spectra.Preliminary bioassay showed that the inhibition rate of some compounds were 100％ at 100 mg/L against Abutilon theophrasti and Digitaria adscendens.