N-2-(4,6-二甲氧基嘧啶-2-氧基)苯亚甲基取代胺类衍生物的合成及除草活性

Synthesis and herbicidal activity of N-2-(4,6-dimethoxypyrimidin-2-yloxy) benzylidene substituted amine derivatives

摘要: 以水杨醛为原料,经取代、加成和消除反应合成了6个标题化合物(3a~3f),其中4个(3a~3d)为新化合物,其结构经核磁共振氢谱、质谱和元素分析确认。初步的除草活性测试结果表明,在有效成分150 g/hm2的剂量下,除化合物3f对稗草Echinochloa crus-galli的抑制率为55%外,其余5个化合物对供试杂草的抑制率均在80%以上,部分化合物对稗草、早熟禾Poa annua、反枝苋Amaranthus retroflexus或小藜Chenopodium album的抑制率达100%。

Abstract: Six title compounds(3a-3f) were synthesized using 2-hydroxybenzaldehyde as starting material by substitute reaction,addition reaction and elimination reaction.Thereinto,3a-3d were new compounds.All of the synthesized compounds were confirmed by 1H NMR,MS and elemental analysis.The preliminary bioassay results showed that the inhibition rate of synthesized compounds to the Echinochloa crus-galli,Digitaria sanguinalis,Bluegrass,Amaranthus retroflexus and Chenopodium album reached 80%,except 3f to the E. crus-galli was 55% at the application rate of 150 g a.i./hm2.The inhibition rate of some of the compounds to E. crus-galli,Poa annua,A. retroflexus or C. album reached 100% at the application rate of 150 g/hm2.