Abstract: Gas chromatography-tandem mass spectrometry(GC-MS/MS)was used to analyse organochlorine pesticides and polychlorinated biphenyls in plants.The sample was cleanup by SPE of Carb/NH2,the target compound can be eluted by 20 mL solvent.It can remove most of the pigment and fatty acid.The method was simple,fast and saving money.The average recoveries of 25 compounds were ranged from 66.6% to 113.1%.The relative standard deviation(RSD%)for all the compounds were ranged from 4.1% to 14.1%.The method detection limits(MDL)were between 0.03 and 0.29 ng/g.The sensitivity of this method was high,and can meet the needs of environmental investigation.The concentration of PCB28 can reach to 108 ng/g in the plant samples in pollution zone.It indicated that PCBs can transfer to plants from soil.