宋永婷, 陈际达, 夏柯, 王天会, 张谦, 张翠. 固体增溶/分散技术制备啶虫脒可溶粒剂[J]. 农药学学报, 2013, 15(3): 344-348.
    引用本文: 宋永婷, 陈际达, 夏柯, 王天会, 张谦, 张翠. 固体增溶/分散技术制备啶虫脒可溶粒剂[J]. 农药学学报, 2013, 15(3): 344-348.
    SONG Yongting, CHEN Jida, XIA Ke, WANG Tianhui, ZHANG Qian, ZHANG Cui. Preparation of acetamiprid soluble granule with solid solubilization/dispersion technology[J]. Chinese Journal of Pesticide Science, 2013, 15(3): 344-348.
    Citation: SONG Yongting, CHEN Jida, XIA Ke, WANG Tianhui, ZHANG Qian, ZHANG Cui. Preparation of acetamiprid soluble granule with solid solubilization/dispersion technology[J]. Chinese Journal of Pesticide Science, 2013, 15(3): 344-348.

    固体增溶/分散技术制备啶虫脒可溶粒剂

    Preparation of acetamiprid soluble granule with solid solubilization/dispersion technology

    • 摘要: 为了实现对难溶或微溶农药的高效利用,并满足速效、低毒和绿色环保的要求,采用医药研究中常用的固体增溶/分散技术,以聚乙二醇10000为固体增溶/分散介质,TANEMULCON1为分散剂,氯化铵为崩解剂,经混合造粒制备了啶虫脒可溶粒剂。当配方(以质量分数计)为啶虫脒30%、PEG10000 60%、分散剂TANEMULCON1 4%、氯化铵补足至100%时,啶虫脒可溶粒剂具有性质稳定、崩解速率快、能形成稳定的真溶液的特性。表明固体增溶/分散技术是将难溶于水的农药制备成可溶粒剂的一种简单、优良的新方法。

       

      Abstract: To enhance the utilization ratio of water-insoluble or sparingly soluble pesticides,and meet the requirements of fast-action,low toxicity as well as environment protection,solid solubilization/dispersion technology was explored for preparing soluble granules from water-insoluble or sparingly soluble pesticides.It was possible to prepare soluble granules with acetamiprid when polyethylene glycol 10000,TANEMULCON1 and ammonia chloride were used as solid solubilizing/dispersion carrier,dispersant and disintegrant,respectively.The optimized formula in weight percentage was acetamiprid 30%,polyethylene glycol 10000 60%,TANEMULCON1 4%,and ammonia chloride of the others.It was showed that the acetamiprid soluble granule of optimized formula was stable for storage,fast disintegration and available to form stable true solution in water.The results suggest that solid solubilization/dispersion technology is a simple,excellent tool for prepareing water soluble granules from insoluble pesticides technical meterials.

       

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