Residuedeterminationof15carbamatesandtheirmetabolitesinChinesecabagesandpakchoibyQuEChERS-ultrahighperformanceliquidchromatography-QDamassspectrometry

A rapid method for the residue determination of 15 carbamates and their metabolites in Chinese cabage and pakchoi by ultra high performance liquid chromatography-QDa mass spectrometry (UPLC-QDa MS) was established. Sample pretreatment was based on the QuEChERS method. The target substance was extracted with acetonitrile and purified with multi-functional needle filter (MFF) . Column CORTECS^® T3 (3.0 mm × 150 mm, 2.7 μm) was used in the chromatographic separation, and QDa mass spectrometry with single ion scan mode analysis was used to detect pesticides. The results showed that a good linear relationships (r > 0.99) in two matrices were obtained for 15 pesticides and their metabolites in the range of 0.001-0.1 mg/L. The recoveries of the target compounds in two matrices were both 68%-120%, and the RSDs were both less than 15% (n = 3) . The limits of detection (LOD, S/N≥3) ranged from 0.001 to 0.004 mg/kg. The limits of quantitation (LOQ, S/N≥10 and recovery in the range of 60%-120%) were 0.005-0.01 mg/kg. These results indicated that the developed method was accurate, rapid and stable, and suitable for the detection requirements in the grass-roots unit.