Research,advancementandprospectofmolecularlyimprintedpolymersfororganophosphoruspesticideresidues

In order to fight the pollution caused by the organophosphorus pesticide residues in soil and water, the molecular imprinting technology has been widely applied in the detection of pesticide residues. The research background of organophosphorus pesticides molecularly imprinted polymers (MIPs), the basic principles and classification of molecular imprinting techniques, the application of computational chemistry in screening and optimizing virtual templates and functional monomers, the preparation and application of organophosphorus pesticides MIPs and other relative content were reviewed. Due to the unique characteristics of structural predictablity, specific recognition and applied universality, MIPs could be widely used in many fields such as optical sensing, chemical sensing, electrochemical sensing, photoelectric sensing, mass sensitive sensing, biomimetic catalysis and sample pretreatment. The molecule simulation softwares, such as Discovery Studio, HyperChem and Gaussian, could be used to calculate the dominant conformation and the lowest energy of template (virtual template), functional monomer and their complexes, and to quantify the binding energy of the complexes for screening the virtual template and functional monomer. Combining computational chemistry with experimental research, organophosphorus pesticide residues MIPs will have further development in many fields including in-situ chromogenic sensing, high-throughput screening of pesticide residues in agricultural products, and automated detection aided by computer.