Antifungal activity of compound 1S,2R-((3-bromophenethyl)amino)-N-(4-chloro-2-trifluoromethylphenyl) cyclohexane-1-sulfonamide against Botrytis cinerea and its mode of action

The antifungal activity of sulfonamide compound 1S, 2R-((3-bromophenethyl)amino)-N-(4-chloro-2-trifluoromethylphenyl)cyclohexane-1-sulfonamide (SYAUP-CN-26) against Botrytis cinerea was determined and its mode of action for controlling diseases was investigated. The results showed that SYAUP-CN-26 inhibited hyphal growth and spore germination of some plant pathogenic fungi, especially for B. cinerea with the EC₅₀ value of 1.82 μg/mL and 14.98 μg/mL, respectively. The spore production, sclerotic production were reduced significantly, and the single sclerotic weigh was increased significantly under the treatment of 20 μg/mL of SYAUP-CN-26. The pathogenicity of B. cinerea treated by SYAUP-CN-26 was significantly lower than that of the control. SYAUP-CN-26 at 200 μg/mL provided control efficacies of 83.11% and 47.52% for protective and curative spraying against tomato gray mold, respectively which showed that SYAUP-CN-26 possessed better protective activity than curative activity.