Research progress of the resistance to succinate dehydrogenase inhibitors

Succinate dehydrogenase inhibitors (SDHIs), targeting succinate dehydrogenase complex, have gradually become the third largest group of fungicides in the world after quinone outside inhibitors (QoIs) and ergosterol biosynthesis inhibitors (EBIs). In recent years, the market share of SDHIs is increasing yearly, and new members are emerging, playing a vital role in the chemical control of plant diseases. However, due to the single action site of these fungicides, fungicide resistance has become a key scientific issue that restricts the development and scientific application of these fungicides. In this paper, the development, products, occurrence and development of resistance, molecular mechanism and application status of SDHIs were reviewed. Together with the latest research achievements from the author's laboratory, the research on target biology and application technology was summarized, to provide references for the innovation and application of higher activity SDHIs.