Research progress on gibberellic acid biosynthesis based on metabonomics

Gibberellic acid (GA) is a widely-used hormone that governs plant growth. At present, GA used in agricultural production is mainly from the liquid fermentation of the fungus Gibberella fujikuroi, but the yield is far from meeting the market demand. Metabonomics, as an important branch of system biology, has attracted extensive attention and made significant progress in the field of microbiology in recent years. This paper reviews the research progress at home and abroad in the fields of the type, production, application, and research process of GA, the concept, advantage, research technique, determination of GA on metabonomics, and the effect of genetic modification, abiotic stress, precursors on the biosynthesis of GA. The combined application of multiple omics related to the efficient synthesis of GA has also been prospected. It provides ideas for the further improvement of GA production in industrial production.