Research progress on the stereoselective bioactivity and toxicity of chiral pesticides

Chiral pesticides have attracted much attention due to enantiomeric differences in biological activity, toxicity and environmental behavior. It is significant to understand the stereoselectivity of enantiomers for developing highly active pesticides and reducing dosage. This review focus on the stereoselective effects of enantiomers of chiral pesticides, thoroughly investigated the enantioselective biological activitiy and toxicity selectivity, and sort it out, the bioactivity, toxicity and environmental risk of enantiomers of chiral pesticides were reviewed. This review described the chronic toxicity of chiral pesticides to non-target organisms, such as oxidative stress and endocrine disruption, and pay attention to the rules and mechanisms of stereoselectivity, in order to provide reference for the development of environmentally friendly and efficient chiral pesticides, the risk assessment and management of chiral pesticides, and the stereoselectivity mechanism of chiral pesticides.