Synthesis and acaricidal activity of methoxylcarbamates containing substituted 2-phenylpyridine moieties

Nine novel methoxylcarbamates containing substituted 2-phenylpyridine moieties were synthesized from hydroxyphenylboronic acid and substituted 2-bromopyridine via Suzuki cross-coupling reaction and nucleophilic substitution sequence. Their structures were characterized by IR,1H NMR and ESI-MS. The preliminary bioassay showed that some compounds exhibited excellent lethality against Tetranychus cinnabarinus at 500 mg/L. The results indicated that above methoxylcarbamates can serve as potential acaricidal lead compounds.