Hua Dong-mei, Yuan Guang-yao, Chen Wan-yi. Synthesis of Alkyl 1-Aryl-1,4-Dihydro-4-Oxo-6-Methylpyridazine-3-Carboxylates[J]. Chinese Journal of Pesticide Science, 2001, 3(2): 81-82.
    Citation: Hua Dong-mei, Yuan Guang-yao, Chen Wan-yi. Synthesis of Alkyl 1-Aryl-1,4-Dihydro-4-Oxo-6-Methylpyridazine-3-Carboxylates[J]. Chinese Journal of Pesticide Science, 2001, 3(2): 81-82.

    Synthesis of Alkyl 1-Aryl-1,4-Dihydro-4-Oxo-6-Methylpyridazine-3-Carboxylates

    • In order to get a convenient method for preparation of pyridazinone carboxylate, 1-aryl-1,4-dihydro-4-oxo-6-methyl pyridazine-3-carboxylic acids have been converted to alkyl esters in good yieds by heating them with dialkyl phosphite at 120~30 ℃ for 4 h.
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