Synthesis and Bioactivities of Novel Substituted Pyridinylmethylimino-thiazolidines and Oxazolidines Derivatives
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Abstract
Based on the structure of Trehazolin, one of natural trehalase inhibitors, pyridinylmethylimino-thiazolidine and oxazolidine compounds were designed and synthesized through reaction of pyridinylmethyl isothiocyanate with appropriate amine and followed by cyclization under HCl and HgO. Their structures were confirmed by using IR, 1H NMR, HRMS. The insect-flight inhibitory bioactivity was given.
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