Synthesis and Bioactivity of a Series of Novel Hydrazone Derivatives

In search of novel pesticide compound with high bioactivity,fourteen new N-3-(N-methoxy-N-methyl-amino)-1-arly-propylidene-hydrazazide derivatives have been designed and synthesized by the reaction of N- -O,N-dimethyl-hydroxylamine with different acyl chlorides. Their structures have been confirmed by 1H NMR and elemental analysis. The preliminary biological activity showed that some compounds possessed insecticidal activities against Culex pipiens pallens and Leucania separata Walke. The mortality ratio of some compounds against C. pipiens pallens coqillett were 95%~100% at concentration of 50 mg/L. The mortality ratio of c7 against L. separata was 100% at 1 000 mg/L.