Synthesis and Preliminary Bioassay of N-Phenylaminophthalimide Derivatives
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Graphical Abstract
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Abstract
In order to discover novel environmental friendly insecticide,11 no insecticidal activity reported N-phenylaminophthalimide derivatives were synthesized through condensation reaction of substituted phthalic anhydride and substituted phenylhydrazine in glacial acetic acid,and 7 among them were new compounds.The structures of all compounds were confirmed with 1H NMR & LC-MSD,and the crystal structure of A02 was characterized by X-ray crystal diffraction method.The preliminary bioassay showed that some compounds had certain insecticidal activity against Plutella xylostella Linnaeus at 600 μg/mL,and the lethal rate of compound A06 was 84% after 96 hours.
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