Properties of abamectin delivery system loaded bymesoporous activated carbon

The loading properties of mesoporous activated carbon for abamectin were studied to determine its potential as the carrier of abamectin.Physical properties of mesoporous activated carbon were characterized by scanning electron microscope,specific surface area analyzer and particle size analyzer.Drug-loading capacity of mesoporous activated carbon was compared with other conventional pesticide carriers,and the adsorption kinetics,sustained- release properties and resistance to UV degradation of the drug delivery system were analyzed and evaluated.The results showed that the trial mesoporous activated carbon were irregular spherical particles with specific surface area of 1 719.25 cm2/g,pore volume of 0.043 cm3/g and average pore diameter of 4.80 nm and its drug-loading capacity for abamectin reached 220.6 mg/g and was significantly excellent over other conventional pesticide carriers.The adsorption processes followed a pseudo second-order kinetic rate equation.Drug release time was extended from 90 h to 672 h,which may significantly extend the duration of drug.The drug degradation rate was 77% in the original drug of abamectin,while only 31% decomposed under UV radiation in abamectin delivery system with mesoporous activated carbon,which showed that mesoporous activated carbon effectively inhibited the photo-degradation of the drug.These results indicated that mesoporous activated carbon can be used as drug carrier for abamectin to improve properties of sustained-controlled release,dispersity in water and photo- stability.