Dietary intake and its risk assessment of triazophos residue

Based on the principle and method on pesticides residue dietary intake and risk assessment proposed by Joint FAO/WHO Meeting on Pesticide Residues (JMPR),adjust coefficient of food intake,safety margin of acute risk and consumer protection level were introduced,an assessment method of dietary intake risk and consumer protection level was established that is suitable for present available data in China.A risk assessment of triazophos dietary intake was carried out by calculation of national estimated daily intakes (NEDIs),national estimated short-term intakes (NESTIs) and risk quotient (RQ) using supervised residue trial data.The result showed that it may come up that unacceptable chronic dietary intake risk for all kinds of people, RQ is 2.1-6.2,and acute dietary intake risk of apple,cabbage,rice and wheat meal, RQ is respectively 14.2-34.3、8.2-17.0、2.9-4.7 and 2.8-4.0.An assessment of consumer protection level was carried out by calculation of theoretical maximum daily intakes (TMDIs) and theoretical maximum short-term intakes (TMSTIs) using existing maximum residue limits (MRLs) of triazophos in China.The result showed that consumer protection level (CPL) is unacceptable in existing all 7 MRLs to chronic dietary intake risk for the group of age 2-10, CPL is 0.6-0.8,and MRLs of cabbage,zucchini,citrus and apple to acute dietary intake risk for children of age 4-6 and adult of age 30-44 and MRL of litchi for children of age 4-6, CPL is respectively 0.2-0.4、0.3、0.1-0.2、0.1-0.2 and 0.6.It proposed that revising triazophos MRLs of citrus sarcocarp and litchi sarcocarp to 0.02 mg/kg and 0.05 mg/kg respectively;adjusting good agricultural practice (GAP) of triazophos application on rice,extending pre-harvest interval (PHI) to 60 d;withdrawing application registration of triazophos on cruciferous vegetables,zucchini and apple;setting MRLs of vegetables,apple and other animal and plant products without application registration to 0.01 mg/kg or nearby limit of determination;carrying out strict supervision and control to illegal use of triazophos.