Determination of nonylphenol polyethoxylates and its metabolite nonylphenol in banana by UPLC-MS/MS

In order to study the residues and safety of pesticide adjuvant nonylphenol ethoxylate(NPnEO)in food,a quick and sensitive analytical method for nonylphenol ethoxylate and its metabolite nonylphenol in banana was established with UPLC-MS/MS.The samples were extracted by acetonitrile and cleaned by solid phase extraction column.Several UPLC-MS/MS conditions that included the mobilephase,monitor ions and the selection of calibration of the measurement were studied.The recovery ranged from 75% to 117% at three spiking levels from 5 -40 μ g/kg with relative standard deviations of 3.2%-9.6% ,meanwhile,the limit of detection of nonylphenol ethoxylate were 0.005-0.04 μ g/kg and nonylphenol was 0.5 μ g/kg.The method was sensitive and rapid.