Synthesis and antifungal activity of novel strobilurin compounds containing 2(1H)-quinolinone

Eleven novel strobilurin compounds were synthesized from(E)-methyl 2-2'-(bromo-methyl)phenyl-3-methoxyacrylate and 2(1H)-quinolinone as materials via etherification,etc.The structures of all compounds were confirmed by IR,ESI-MS,1H NMR.Antifungal activity test showed that the compound 5a,5d and 5e exhibit certain inhibiting effect against all the tested strains at the concentration of 100 mg/L,and 5a showed 100% inhibition rate against Pyricularia grisea.