Synthesis and nematocidal activity against Panagrellus redivivus of 3'-alkyl- α -terthiophene

Starting from 3-bromothiophene,a series of 3'-alkyl- α -terthiophene derivatives(8-16) were synthesized via Kumada coupling reaction and Suzuki coupling reaction as key steps.Five of them were first reported.Their structures were identified by 1H NMR,MS and elemental analysis.The illumination method was used to test the nematocidal activity against Panagrellus redivivus of these compounds for the first time.The results showed that these compounds exhibited more potent nematocidal activity except compound 13,under the condition of a concentration of 50 μg/mL,the light intensity of 2 000 lx,light time of 72 hours.The nematocidal activity of these compounds was above 85% except compound 13.